Modified-release 3D printed capsules
Université Libre de Bruxelles - Réseau LIEU - 09/18/2020
The invention describes the production of functionalized capsules by 3D printing to modify the release of drugs. It proposes to substitute the commonly used dipping method of coating in compounding pharmacies, hospital and preclinical studies by a 3D printing method of production as the efficacy of such coating method is known to be erratic and may lead to potential therapeutic failure. The invention relates to 3D printing techniques which represents an elegant tool for designing simple, accurate, cheap, structured and tailored drug delivery systems in pharmaceutics. Here, 3D printing is used to produce unique modified-release (e.g. enteric, colonic, sustained release) capsules ready-to-use.
More robust process – less erratic in term of efficacy One-step process Automatic process No use of organic solvents Ability to prepare magistral preparations as well as small batches for pre-clinical studies with sustained-release properties
New method for the production of functionalized capsules by 3D printing used to modify the release of drugs.