INJECTABLE SOLUTION FOR CELL PRESERVATION

ETABLISSEMENT FRANCAIS DU SANG - 06/03/2021

Description

Hematopoietic stem and progenitors cells cannot be preserved for long time at +4°C. They are especially vulnerable after ex vivo expansion. Before injection to the patient, these cells are usually resuspended in human serum albumin solution, which does not ensure their conservation over several hours. It is possible to preserve hematopoietic cells at +4°C without freezing by more complex media, which are, however, not injectable. The EFS proposes an injectable solution to preserve functional hematopoietic stem and progenitors cells, which avoids rinsing step before their injection to the patients.

Benefits

• Injectable solution of hematopoietic graft to patients, without previous rinsing • All components of the solution are approved as injectable by the drug approval administrations (FDA, EMA, ANSM) • Solution compatible with any kind of injection (intravenous, intramuscular….). • The viability and the functionality of stem cells compatible with therapeutic uses • Can be used for: Fresh cells, previously frozen cells or ex vivo expanded cells

Innovations

Solution which preserves the quality / quantity and the functionality of cells during at least 48 hours at 4°C.

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