AN INNOVATIVE PROCEDURE FOR PRESERVING CELLS, TISSUES OR ORGANS IN HYPOTHERMIA
ETABLISSEMENT FRANCAIS DU SANG - 06/03/2021
A conservation procedure which improves the cell survival and maintains functional capacities of cells, tissues and organs without freezing step. This procedure improves the quality of graft. This procedure involves a pre incubation of cells, in moderate hypothermia, under an hypoxic and/or hypercapnic atmosphere, before being transferred into strict hypothermia. APPLICATIONS: • Short to mid term cells preservation • Storage and transport of cells, tissues or organs
• The quality of preserved cells is improved: The functional capacity and the proliferation capacity of preserved cells is superior compared to those cryopreserved. • Compatible with cells transportation and storage. • Useful for various types of cells, tissues or organs. • Short to mid term preservation of cells, tissues or organs. • Avoiding freezing step. • Cryoprotective agents are not required. • Compatible with human cell therapy requirements
Cryopreservation is the most common method used for cells preservation. Nowadays, there is no procedure for short to mid term cells preservation before transplantation without freezing step. The EFS proposes a new procedure which extends cell conservation time to 72h in hypothermia conditions improving the quality of preserved cells, tissues and organs.