Offres de technologies

Simulation speedup - accélérateur de calcul numérique

CONTEXTE Aujourd’hui, dans le monde de la simulation numérique, différentes techniques existent. Dans le cas des études de sensibilité (Design Of Experiment) les simulations permettent de dimensionner un produit afin de garantir sa fonctionnalité e...

Neuron reprogramming - new functional corticospinal motor neurons

BACKGROUND There is need for corticospinal motor neuron replacement in various therapeutic fields: Post-stroke rehabilitation: while there is a number of acute-phase stroke treatments, there are currently no therapies available for patients with a...

Uv boosting plant defenses - innovative ultraviolet lamps to stimulate natural defense mechanisms of plants

BACKGROUND Reducing risks for human health and the environment is a major issue. The “EcoPhyto Plan” was launched by the French Government to reduce the use of pesticides in France by half by 2025 while maintaining high yields as well as high qualit...

Adaptable antennas - a multiband system antenna with maximal decoupling and easy configuration

BACKGROUND The wireless market leads to design miniaturized antenna systems for better integration but without degrading performances. As systems become multi-standards (GPS, LTE, WIFI), antenna systems must be multibands, efficient and affordable....

Ocr preprocessing - enhanced binarization of highly damaged images prior to ocr processing

BACKGROUND Existing OCR solutions show limits with distorted or degraded supports and require an extra step of binarization that is resources-consuming. OCR PREPROCESSING is a lightning-fast algorithm dedicated to image binarization, which was speci...

3d autofocus - accurate 3d autofocus system for microscopes

BACKGROUND Autofocus solutions are available for microscopy applications to compensate for spatial drifts induced by mechanical or thermal fluctuations. These solutions are based on laser or LED light reflection at an interface; they all suffer from...

Sulfate radical - sulfate radical-advanced oxidation process (sr-aop)

BACKGROUND Contamination by organic non-biodegradable pollutants, of both surface water and ground water, rises serious environmental concerns (water quality, environmental impact, feminization of male fishes…). Biological treatment used in wastewat...

Detect person - vision system for hazardous point protection

BACKGROUND Aiming at preventing accidents, this innovation relies on real-time image processing of a hazardous point video surveillance. Automated detection of presence or absence of a specific patterned and/or colored safety vest, complying with a...

3d virtual - reality virtual plugin for complex virtual reality systems

BACKGROUND Today, virtual reality is increasingly used in video games or in new products design  for automotive and naval sectors, architecture, ... To make virtual spaces, it is necessary to use 3D engines for the development of these environments,...

3d virtual - plugin pour le déploiement d'applications 3d sur des dispositifs complexes de réalité virtuelle

CONTEXTE Aujourd’hui, la réalité virtuelle est de plus en plus utilisée dans la conception de nouveaux produits; que soit dans le secteur de l’automobile, naval ou grands public, réaliser des espaces virtuels nécessite d’utiliser des moteurs 3D perm...

Lcg-spectro - multichannel spectrometer having a sensitive layer with a lateral composition gradient

BACKGROUND Spectrometers without dispersing elements have been developed to reduce their size and weight. These spectrometers comprise a matrix of photodetectors, above which is disposed a set of filters. Each photodetector is equipped with a filter...

Lcg-spectro - spectromètre multicanale munie d’une couche photosensible à gradient latéral de composition

CONTEXTE Des spectromètres sans éléments dispersifs ont été développés afin de réduire leur taille et poids. Ces spectromètres sont basés sur l’utilisation de filtres optiques déposés sur une matrice de photo-détecteurs. Chaque photo détecteur est é...

Soft mixer - a new industrial mixer blade-free

CONTEXT Most of the available mixers have propellers or blades of various shapes and size. But for specific use in pharmaceutical, food & beverage or chemical industry, these blades induce shear and/or cavitation issues, which may damage cells or m...

Soft mixer - mélangeur sans pales

CONTEXTE La plupart des mélangeurs utilisent des pales ou des hélices tournantes de diverses formes. En particulier pour certains procédés comme la fabrication de produits pharmaceutiques, agroalimentaires ou chimiques, ces pales sont problématiques...

Shark anastomosis connector - shorten and safer surgical vessel sutures

BACKGROUND Vascular anastomosis still requires non-absorbable thread and overlock for sutures. Although this approach is broadly used, it is time consuming, surgeon-dependent and flawed with risks of stenosis or leaks. According to the latest estim...

Kinase inhibitors & cancer - potentiating anti-pd1 antitumor immunotherapy

BACKGROUND Immune-checkpoint blockades targeting CTLA-4, PD1, PDL-1 are major breakthroughs in cancer therapy, increasing overall survival. The launch of these premium-priced metastatic immunotherapies will extend treatment duration and replace chea...

Anti-melanoma - new chemical entity for melanoma treatment

BACKGROUND There is high unmet medical needs metastatic melanoma, with a 5 years survival rate at stage IV of 15-20%. Immunotherapy gives between 15 and 30% of responses. Anti-BRAF treatments trigger resistance within a couple of months and there is...

Lift double pulse - procédé d'impression haute résolution par laser

CONTEXTE Le développement de l’électronique imprimée et de l’électronique sur support souple passe par la mise au point de dispositifs d’impression numérique fiables,  permettant d’imprimer des structures 2D de dimensions micrométriques. La princip...

Influenza antivirals - novel target for the treatment of influenza virus

BACKGROUND Despite vaccination, 5 million people are affected each year by the influenza virus in the world, causing more than 500,000 deaths annually. Current antivirals (neuraminidase, hemagglutinin and M2 protein inhibitors) are no longer effect...

Influenza antivirals - nouvelle cible pour le traitement de la grippe

CONTEXTE 5 millions de personnes sont atteintes chaque année par le virus de la grippe dans le monde, malgré la vaccination, causant plus de 500,000 décès annuels. Les antiviraux actuels (inhibiteurs de neuraminidase, hémagglutinine et protéine M2)...

Gdc lensless endoscope - in vivo imaging system with a cellular scale for a preclinical diagnostic

CONTEXT Modern endoscopy requires solutions for acquiring images at the proximal end of endoscopes while limiting the space requirement at the distal end. Lens less endoscopes can meet these new needs. In these systems, the light beam is focused by...

Gdc lensless endoscope - système d’imagerie in vivo à l’échelle cellulaire pour le diagnostic préclinique

CONTEXTE Contrairement à un endoscope classique, les systèmes d’endoscopie sans lentille peuvent être miniaturisés. Cependant, les systèmes actuels, tels que l’imagerie à fluorescence bi-photons, ne permettent pas de réaliser des images dans des mod...

Smartsens - all-in-one ultra sensitive and very low concentration pollutant detecting devices

BACKGROUND Urbanization and increased human activities gradually lead to the degradation of the environment. It causes adverse effects on human health by the release in food, water, air or soil of various pollutants, including pharmaceutical & perso...

Gamma speckle - optical diagnosis of corneal defects

BACKGROUND Ophthalmologists usually conduct a simple analysis with biomicroscopy to diagnose whether the cornea is damaged. However, this technique does not allow a precise analysis of the cornea, including for detecting little damages not visible...

Gamma speckle - diagnostic optique de l'état de la cornée de l'œil

CONTEXTE Les ophtalmologistes procèdent généralement à une simple analyse de visu de la cornée, par l’intermédiaire de la biomicroscopie (ou lampe à fente), pour diagnostiquer si elle est abîmée ou non. Néanmoins cette technique ne permet pas une a...

2c-dls - detection of analytes in solution by using nanoparticles as light scattering enhancers

BACKGROUND Analytes detection (e.g. proteins, nucleic acids, DNA, bacterial fragments…) is important for both molecular biology research and medical applications. However, the existing detection methods show a low signal to noise ratio, that result...

Scatterometer without movement - roughness measurement system for « extra smooth » surface

BACKGROUND Surface quality controls are important for manufacturing processes including the machining of mechanical parts for the automobile or else for manufacturing of semiconductors or optical components. Today, surface roughness measurements ar...

Diffusomètre sans mouvement - système de mesure de rugosité pour surface « extra lisse »

CONTEXTE Le contrôle de la qualité d’une surface est important pour un grand nombre de processus de fabrication tels que l’usinage de pièces mécaniques pour l’automobile ou encore dans la fabrication des semi-conducteurs et des composants optiques....

Megadalton detector - ion detection with applications to very large, charged molecules without mass limitation

BACKGROUND This innovation analyzes on different fragments of a deliberately segmented molecule, in a complex experimental process. This original approach allows new medical applications: for macromolecules rapid detection (proteins and viruses for...

Curcuminophore - complexes with high fluorescence quantum yield for bioimaging

BACKGROUND Finding new compounds having all the characteristics to become attractive candidates as fluorescent reporters is complex. Especially, dyes emitting in the Near Infrared (NIR) using two-photon excitation in the NIR region are of great inte...

Cassic - method of manufacturing a silicon carbide micromechanical structures with cavities

BACKGROUND Sensors are frequently used in hostile environments (high temperatures or pressures, extreme chemical conditions). For such applications, resistant materials such as silicon carbide (SiC) are suitable candidates. However, due to its chemi...

M-cube - metamaterial antenna for ultra-high field mri

BACKGROUND The clinical use of Ultra High-field (UHF) MRI scanners is drastically limited due to the lack of homogeneity and to the Specific Absorption Rate (SAR) of the Radio Frequency (RF) fields associated with the magnetic resonance. The major...

Adita - accumulation of ions in a linear radiofrequency trap

BACKGROUND Transporting charged particles between different traps has become an important feature in high-precision spectroscopy experiments. A major issue during transport is the heating of the transferred atoms or molecules and the speed of the sh...

Triazoles & cancer - triazole derivatives to fight myelodysplastic syndromes and acute myeloid leukemia

BACKGROUND Myelodysplastic syndromes (MDS) are estimated to occur at a rate between 4 and 5 for every 100,000 people in the world. Approximately 13,000 people in the United States and 2,500 in France are diagnosed each year. 40% of MDS patients hav...

Handwritten / printed text discrimination using agent technology (hapedate)

Scanned documents can contain handwritten text, such as annotations, signatures, or filled-in blanks in forms. Identifying those handwritten parts from printed parts is a preliminary step in the treatment chain of the document.To this end, state-of-t...

Revêtement sol-gel hybride pour application tribologique

DESCRIPTION : Procédé de fabrication d’un revêtement de surface lubrifiant, formé par un réseau solide incorporant du carbone à l’état dispersé & piégé au sein de ce dernier La matrice minérale est réalisée à partir de précurseurs choisis parmi l...

Widefield : optical module for near-eye display in augmented reality

Optical module for near-eye display in augmented realityy     TECHNOLOGY   Waveguide-based optical system to guide image from side of the head to the eyes See-through to allow image super-imposition onto the real world and augmented reality...